Donald Little III

Disciplines/Field of Instruction

• 生物学
• 遗传学

Degrees Received

• Ph.D. Cancer 生物学, University of Michigan, 2021.
• B.S. 遗传学; Minor: Wildlife Science, Purdue University, 2015.

Publications

• 博尔赫斯,K.S.*, Little III, D.W.*, Magalhes, T.A., Ribeiro, C., Basham, K.J.， Azova S., O’Connell, A.E., Guagliardo, N.A., Barrett, P.Q., Berbur, M., 汉、维.R., Turcu, A., Breault, D.T., 和 Hammer, G.D. Non-canonical Wnt signaling is critical for adrenal development 和 disease. In preparation. *co-first author.
• Little III, D.W., Dumontet, T., LaPensee, C.R., 和 Hammer, G.D. (2021). β-catenin in adrenal zonation 和 disease. Molecular 和 Cellular Endocrinology 522 (15). doi: 10.1016/j.多国评价.2020.111120.
• van Rooyen, D., Lerario, A.M., Little III, D.W., Ullenbruch, M.R., Taylor, M.J., Gomez-Sanchez, C.E., Hammer, G.D., 和 Rainey, W.E. (2024). Chronic activation of Gq signaling induces Cyp11b2 expression in the zona fasciculata 和 hyperaldosteronism. Molecular 和 Cellular Endocrinology 585(24): 112176.
• 汉、维.R., 博尔赫斯,K.S.， Finco，我., LaPensee, C.R.梭伦，A.， Rege， J., Little III, D.W.， Else， T., Almeida, M.Q., Apfelbaum, A.文科，M., Wakamatsu, A., Mariani, B.M.P., Latronico, A.C., Mendonca, B.B., Zerbini, M.C.N., Fragoso, M.C.B.V., Lawlor, E.R.哦，嗨，R., Rainey, W.E., Venneti, S.玛丽，S.K.N., Giordano, T.J., Breault, D.T., Lerario, A.M.*, 和 Hammer, G.D.*. Repressive epigenetic machinery coordinate SF-1/β-catenin-dependent differentiation in aggressive adrenocortical carcinoma. *co-senior author. Cancer Research 2023 Jul 5;83(13):2123-2141. doi: 10.1158/0008- 5472.CAN-22-2712.
• Maiyuran, N. 和 Little III, D.W. (2023). The impact of race 和 gender on the prognosis of breast 和 pancreatic cancer. Research Archive of Rising Scholars. http://doi.org/10.58445/rars.235.
• Collings, C.K., Little III, D.W., Schaefer, S.J., 和 Anderson, J.N. (2019). HIV chromatin is a preferred target for drugs that bind in the DNA minor groove. 《bwin体育》 14 (12):e0216515. doi: 10.1371/journal.玉米饼.0216515.

Presentations

• Fritcha E. 和 Little III, D.W. Psychiatric Genetic Counseling for Adolescents: A Review of Current Research Methods 和 Perspectives. Second Annual State of Michigan Clinical 遗传学 Conference, Gr和 Rapids, MI. Abstract submitted.
• Little III, D.W., 博尔赫斯,K.S., Basham, K.J., Azova, S., O’Connell, A.E., Dumontet, T., LaPensee, C.R., Breault, D.T., 和 Hammer, G.D. WNT2B is Essential for Adrenocortical Progenitor Cell Fate 和 Zona Glomerulosa Identity In Vivo. ENDO 2021, virtual. Selected for Outst和ing Abstract Award.
• Little III, D.W., Basham, K.J., 和 Hammer, G.D. WNT2B Regulates Adrenocortical Progenitor Cell Fate 和 Zona Glomerulosa Identity In Vivo. ENDO 2020, San Francisco, California. (Canceled due to COVID-19). Selected for Endocrine Society Presidential Poster Presentation 和 Outst和ing Abstract Award.
• Little III, D.W., Basham, K.J., 和 Hammer, G.D. Loss of WNT2B in the adrenal capsule leads to reduced adrenal weights 和 cortical proliferation in mice. Cancer 生物学 Program Retreat (2019).
• Little III, D.W., Basham, K.J., 和 Hammer, G.D. Elucidating the role of WNT2B in adrenocortical development 和 homeostasis. Cancer 生物学 Program Retreat (2018).
• Little III, D.W., Basham, K.J., 和 Hammer, G.D. The role of WNT2B in adrenal development 和 homeostasis. Cancer 生物学 Program Retreat (2017).
• Little III, D.W., LaPensee, C.R., 和 Hammer, G.D. Exploring the role of Ccdc80 in adrenal stromal cell adhesion, development, 和 cancer. Cancer 生物学 Program Retreat, 2016. Selected for 3路的地方.

委员会

• Co-Chair, Faculty Summit Committee, Concordia University Ann Arbor, 2023-Present
• Member, Institutional Review Board, Concordia University Ann Arbor, 2023-Present

Awards 和 Distinctions

• Outst和ing Abstract Award - ENDO 2022, National Endocrine Society Annual Conference, Atlanta, GA - Abstract Title: WNT2B Deficiency Results in Hyperreninemic Hypoaldosteronism in Humans 和 Mice.
• Outst和ing Abstract Award - ENDO 2021, National Endocrine Society (virtual) - Abstract Title: WNT2B is Essential for Adrenocortical Progenitor Cell Fate 和 Zona Glomerulosa Identity In Vivo.
• Outst和ing Abstract Award, Presidential Poster Presentation - ENDO 2020, Endocrine Society, San Francisco, CA - Abstract Title: WNT2B Regulates Adrenocortical Progenitor Cell Fate 和 Zona Glomerulosa Identity In Vivo. Conference canceled due to COVID-19.

Memberships

• National Audubon Society, 2020-Present
• Endocrine Society, 2016-2022
• American Association for the Advancement of Science (AAAS), 2015-2018